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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8190e86fe20d53d7d1aca9dc65654706c9196d693eeaa15cb49c6ac0f1d77586' 
  AND token = 'siAaYSqvD/Q6SF+4RMMwm7XWU+SSStS2Mvd77EjdywE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}