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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a87104cb1c01ef5b8a626cdde12f3a21ccef55f013365e60e07cd81d8fe6d5' 
  AND token = 'XM8st06pw1SRUi8ZmFQI0/LIswltZXNxVxoDKPAhnbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}