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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12ce05ba9a7f1605eb8e510f436673509d82295ba13a49430447b01db0f8aa9' 
  AND token = 'MPpz7OT7aaioyIotavqs8pqMVpkqNiUBw2jVmcLvKSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}