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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4bfcb990a74da29d19e33ecd14904657d6efc9231978fd0d4e49dc9fa1b275' 
  AND token = '5XUJXQOwnOS2ajMItRaOkNipW9KrdNAdi9HT91EUfcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}