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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64aa25b1fcd0e91151aea4d1ef0233d467c41c579f17a168920fca9218ea528' 
  AND token = 'mNb6bMrohieQiB5Q9OOfSgdhHctN6PLovfPDWBBA0qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}