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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2197d513514d5d7a9261abdbc715cf9570fad804b5eabfd14314aee989e8faf4' 
  AND token = '0ZMq8fiJChwtkelggUFgRIZAqotNeN+PAFrYrxtw46U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}