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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545a23208e008a345f5c8f19da8523f24c968f37b4d6532bbfe1c970d85bbd3d' 
  AND token = 'LlCEjD6xs6wqZY5eRhQmh+0TfNLGaMPCR6+W4I+Ka3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}