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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e5b1f41a927dee4891e222121779b284a9fd9669ef492e566c1782c7bbc10d' 
  AND token = 'lm70Us3tojmRuftFjZJwi+yF1N+m+7MG7CK84zrKsu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}