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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6626da91d6eed34160240f8d9cbb92af70e2504da0aa04ef32c1d8b85bb921' 
  AND token = 'mwiXO+yoNdLQxFD87eOVdAnOfgG7xK5SK2pxkA4i8PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}