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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101c435c7bc1a08bf1127b2be2862063f043e793d9f5f772d85a68be1d4874ab' 
  AND token = 'ZNL0UHRbbnZ5cvkxbvT2Ig18/c9Wm42YHm0UKM20AWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}