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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b2e9e3d9d2d40f427da7a18db842628c89958e4d45d6854c53b4ccd35756db4' 
  AND token = 'EsmL6ZgsJWNiFQPcEULG0/Ij5j6CkUxRkIEHNi2C+N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}