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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a2481a8e277cf0bd8aed35aba5c6437c3a162718931e1c061bd4b2636a4ed5' 
  AND token = 'A5NuBzboLxqfVxMNoDvO0TYRtKFYgEz9brGiXE9KsMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}