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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8980dbb53d07945ec6d5c837c208e6ab65217d395b1d7793f8555912c53623b8' 
  AND token = 'fTpF2nnlkOnNzkI2i/fBW0II8tjXyiz/NHrSO9K7GBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}