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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dae8e3a7efaa9448e2d04229fcfcfa7995b75a4b0643f636cbf33a38b6ecdf6' 
  AND token = 'nwIaP2MwN4/KP9o0zCTexnoGLS64bJKyV9Mrbo/abxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}