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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea951069a0b31f52848032d8395304c3c39bd1c3277714c675f1530ae644ee03' 
  AND token = 'kfrOFTn0gbo+DRXZIBI8tDQgCGnwMXsQ4TE0g6YG/D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}