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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ae6fa5d2115769b4d293f8c792c9cca0297196cf17996d0203f2719089bfdc' 
  AND token = 'jTpJzpmP49zTxseIG4kYFJDXofv2cnMCFjj1g7geEB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}