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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17027b4edb46a34078d617a0411540e714723fbbd6d5604e5a036cc7e766b340' 
  AND token = 'YuAbzne5walAX+4blbkNhg/FFB2570SsfHuF81wsISg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}