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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded42f42f88db8ffb7652b18cd77e759e781448b5b3b674499cb0b65a5729813' 
  AND token = '1Nelk9QY18q0mevrEd1D4gw457hm7/9RzgulAAcO0TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}