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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ae0e1dda1089488361315a4ce49780f38b00a4c896bc437da6003135fbdd85' 
  AND token = 'DO3kntQ7DK2p+BtlnEs2Cd8PAf6hXfMt6YLTzXlN4Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}