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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c935326e08a4099f84d5f4469b76507242aec0834bb8e0309ed52267d971a2' 
  AND token = 'HR7HNYPdryvthRrc8ZTrZif+kkLT4X/2ojEXLtpcd1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}