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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677ee19dbbc768a1008ab5c442e21a807bb4a4dc5b0765f7d76dd5f2fbc97546' 
  AND token = 'xBVmGy4KLVkKCDsAjnDe54Tjjr5cQWSSOeHyNn56Qtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}