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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9025ab119d03b4d9f94244729be1b713aa0f1f9aafb886adf6e8ca0efe9de2d4' 
  AND token = '5RP0ylhHIPIz6XcXpvfMI5n2tIcOolMyqkC0n/zdG54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}