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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8280db3dc1ef24d194c79c283c40b72aeae809ef61dc099c795592152f0f60f' 
  AND token = 'EtCDFgpDKk2HpL5EnGdMg9q/U9sJmLJmMI3U/gQ4QhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}