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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5cfd97ab20b5eed40f574574b0ed38debcf8f6df3a236a25ff41f2d690e2a5' 
  AND token = 'XaSWicvaEtOXpUB+AL2UjvsWCsFDVCzwiRy4hBXrua0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}