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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22bdabc11ef0f2d4389c6dea8ac2e6db573fa74e72b368919ca9b63fc9781ab' 
  AND token = 'QlnDv7u9dr5Y02uV8HpAtKwOpsUtC//aRASdExHKQsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}