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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2130f6fb50e3e295f4fc509870e49afe7b20b206508b1b7e0c28f361fa2174' 
  AND token = '8QOzqIBiE8PYSaErULIC1ladA0J71nowg0+1Sq9uiR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}