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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3149301d3565ad62fd149da3f354b6a19954aa3d5cedf53c02cc3b75143898' 
  AND token = 'aqRz5VQC0h0svC/4BY9lyOka49Od5pmI6vHiyDXjA7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}