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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3c227eb380114072ade7a32c7a506e70eb62d3b00916b74b4dc9b5a0c13914' 
  AND token = '37aF3xjBukJ0WMxRQcsu81Yg911XcER9SmDFrmPpiEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}