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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c406666b1f03869e4e907a4d38ef1dfd8c4872ec56c099ff66adf75378f15ecb' 
  AND token = 'RMgaRLeDzbyW8+3DcvvZCAIF6c02/2gtmGw6Vem4pqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}