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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff6cf68d54801393b6ac29f54b994674c2e85acf65a27b3c566e3b43aa41770' 
  AND token = 'Yuh27PoHjQR2lxxinLc74LGmAlMa9UE5LhbMgUSfA6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}