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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43383636cd79d218c3498b805fedb67287b0a67b5526af509db3d74c9dedf524' 
  AND token = 'oXhPW6XHlGkCxcq3cxjHiVnrqV6EXoKoaYnX3S+SI8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}