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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be009f0b923da01c639c3b01c665a4c59d470bc00ba1541aaba2a120710e7ed8' 
  AND token = 'uAD8jfPn++N7OiwI0X3NKgBnPKqYEZNz9tPhoZ8plUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}