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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cb7ce8df19016358cacfa24ab43d529158ed9e3da809b41c1bc021e6022ff9' 
  AND token = '5Bj6q7eZ3w+9lyL1xIE6Mvk4+YgZQcLExI4Jo8VGdkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}