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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1298f37298b1e4bfcf505eff63c7b2d225ae2e0db06aefe44f3823939b5be4fc' 
  AND token = 'BpgARdrNQXhpEwYM2+LHe1DEYh+Wd04FhLR+RJ7HhL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}