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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c6b78aab45cffd3e8b34c40a0355e7ae0a108e4761bd4a9f0fc136cb4678e3' 
  AND token = 'wz12TSDgy+fAX3/o93llOdA8P+SpmGkwljfQFTmwZVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}