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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c811f411911ecf9ac1e9253b4407db5823c3fc790b953a25ac05ecb7fdd2d126' 
  AND token = 'P/z4qGGPjID1NAZ3GIyRr2IXYlKbwjwqAuOHk7T4qXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}