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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e925b6b575998fde62e6b57e2c938cc8dc2d4deedc1e9214a0cbc5afe1422174' 
  AND token = 'GNE5n80zAtk/k4in7BJ+JJoxWDQbm3H8QD8Bh6mlz8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}