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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d7f68fb5198aea9a673d31d0d3294b198f1fd66df4aa7b081947d0609d0773c' 
  AND token = 'TKoiniPmFJmnlpg6OGkIaOotgAkgNw3bLB1j3VfjnoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}