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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ce0ffc95cb8726e51e7149fcf6e963baefc321cfa12d619ed861001b4d7220' 
  AND token = 'QTg2Z2RwiX3yqmraxk7Vzmxs/5tfi6u9u03MZq9GdII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}