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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b8ed865b6bc1bb22f45c10290a532cfd812657255bfe11d29174a1ff6e0f2c' 
  AND token = '/Odx91kXuSKIg+tAfDNgoEpEm7UmipfYM01FfrTU+PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}