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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66371ff6846232e8e45f770ecb64aecf7e8c45c39a4d304ce09c085dde1f430c' 
  AND token = 'hI9RSBY1EmTCkymC81KsWMd4z0wIjjmBQmeP+VfwS/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}