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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec42dee2176d6a5b4de20bec507be6d8dc354bab8f2184d1c2e392a1b5349628' 
  AND token = 'I6pK/YQ+ygp7CNZL4Cd2Ipel2MLlWZeel6fXg9njFPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}