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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43d533675fb2ebc32916cb2edb6f365e66bde127c229c375d558cc2b6a7970b' 
  AND token = 'Og6A/4fELxSXw3PYRjNltA3AopvmT0culrfy8kxr/YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}