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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a30c5efe353c91bcc97be8c127dde380b8bfbb7ba16004d0dfc68502bed54f9' 
  AND token = 'NGuQFmCszbsIGk9Y8QeDcGOUXwQ3eEEu/Ymy8EUX6D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}