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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edf9fe10c230ca069d1e1f4d52efe62300e6cf341db3c8aafdd92cd679d281c' 
  AND token = 'ag61n3Q+qCQk+IOSI/LZWU1yTNLDkXzd78jl00uhbtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}