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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c9327b4c99b0c8bc3ae1efdce1ce7fbb8330596a32d20405ac0a158613d436' 
  AND token = 'EyGqMO0vGSXe+rI/4KgPf+992KA8F4XUPSPT1uWrUdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}