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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df392b1b796675d0ae0697c86e6b0bbdc0d39a5e13adaa16c277ce07fa8f3c5' 
  AND token = 'xQh4/83zfQg9C5V71jVyGcJb0gIf8+CrTcZS/WZF260=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}