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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00afea6b9ebc32fbcf254cea429b58ea103e12d9c3ab359d636d51cfec3f9a4' 
  AND token = 'MT7I1CSo17Gs6+/Aok+t8Yze7GDu4uScxUuUcmZ6JqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}