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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a4506474e3a29a0d6bbbd445e43a07315f4ee6f04d296f23c4d510516b20d00' 
  AND token = 'D65Myxmey9DytLxHYmhmCK9VwXMmtJVnW5JQz/x2JHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}