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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2587dcdb9c0d2e5002ef0e66808206e64c470a11ed5ba8049bcf61c5ace27b43' 
  AND token = '8nIiHSzKcp4L0rrKXd6ezvrDTZNxQJIEL+1MT/I1c4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}